Sonochemistry in organocatalytic enamine-azide [3 2] cycloadditions: A rapid alternative for the synthesis of 1,2,3-triazoyl carboxamides

Xavier, D. M.; Goldani, B. S.; Seus, N.; Jacob, R. G.; Barcellos, T.; Paixao, M. W.; Luque, R.; Alves, D. Ultrasonics Sonochem. 2017, 34, 107-114. http://dx.doi.org/10.1016/j.ultsonch.2016.05.007

The authors described the use of sonochemistry in the organocatalytic enamine-azide [3 2] cycloadditions of β-oxo-amides with a range of substituted aryl azides. These sonochemical promoted reactions were found to be amenable to a range of β-oxo amides or aryl azides, providing an efficient access to new N-aryl-1,2,3-triazoyl carboxamides in good to excellent yields and short times of reaction.